Why Stress Affects Hair: The Cortisol Connection
Learn how elevated cortisol levels disrupt follicle renewal and why stress management supports healthier hair cycles.
This study investigated how chronic stress triggers hair loss through hormonal signaling. Researchers found that high cortisol levels inhibit the activity of hair follicle stem cells.
- Cortisol suppresses growth-promoting molecules in the follicle bulge region.
- Stress activates a protein called GAS6, halting new hair formation.
- Reduced stem cell renewal leads to premature entry into the resting phase.
- Hair regrowth resumed once cortisol levels normalized.
This explains why people experience hair thinning after intense stress. It connects psychology and biology, showing that mental well-being directly affects cellular health.
Animal studies formed part of the experiment; more human trials are needed to confirm the pathway’s timeline.
Scientists are studying cortisol-blocking compounds to prevent stress-induced alopecia.
Citation & Review Team
Full Citation
Hsu YC et al., Nature, 2023.Review Team
Author: Student Editor
Fact-Checker: Dermatology Researcher
Disclaimer
This article is for educational purposes only and not a substitute for professional medical advice.